The overall goal of this research was to gain further insights on the etiology and epidemiology of ABC and anthracnose, which are critical to developing and providing disease management recommendations for the industry. Botryosphaeria branch canker and dieback of avocado (Persea americana Mill.) has expanded in avocado growing areas in recent years and currently represents a threat for avocado production worldwide because of the important economic losses resulting from reduced yield of affected trees and their premature death.